Beilstein J. Org. Chem.2013,9, 2344–2353, doi:10.3762/bjoc.9.269
starting materials, and the excellent yields of products.
Keywords: green chemistry; pyrrole-fusedisocoumarin; reusable solid support; silica sulfuric acid; solvent-free condition; Introduction
Isocoumarins are an important class of naturally occurring lactones [1][2][3], which has attracted the
product formation and greener characteristics than the previous one in many respects such as (a) a less laborious and more step-economical reaction for the library synthesis of pyrrole-fusedisocoumarin derivatives, since the starting materials dihydroxy indenofurans 6 and 7 need only one step for
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Graphical Abstract
Scheme 1:
Synthesis of pyrrole-fused isocoumarins.